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Matthias Karck Selected Research

Custodiol-N solution

10/2022Custodiol-N versus Custodiol: a prospective randomized double-blind multicentre phase III trial in patients undergoing elective coronary bypass surgery.
2/2015Custodiol-N, the novel cardioplegic solution reduces ischemia/reperfusion injury after cardiopulmonary bypass.
4/2010Effects of Custodiol-N, a novel organ preservation solution, on ischemia/reperfusion injury.

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Matthias Karck Research Topics

Disease

31Reperfusion Injury
10/2022 - 06/2007
25Heart Failure
08/2020 - 10/2005
11Ischemia
01/2021 - 05/2002
10Marfan Syndrome (Marfan's Syndrome)
11/2021 - 11/2002
10Myocardial Infarction
10/2020 - 01/2007
9Atrial Fibrillation
01/2022 - 09/2011
9Heart Arrest (Cardiac Arrest)
04/2019 - 10/2009
8Brain Death (Brain Dead)
01/2021 - 10/2011
8Aortic Valve Stenosis (Aortic Stenosis)
01/2019 - 05/2008
7Fibrosis (Cirrhosis)
01/2022 - 12/2012
7Myocardial Ischemia (Ischemic Heart Diseases)
12/2019 - 08/2009
7Aortic Dissection
11/2017 - 11/2003
6Endocarditis
01/2018 - 12/2012
6Thrombosis (Thrombus)
01/2017 - 11/2003
6Hemorrhage
10/2014 - 02/2004
5Cardiogenic Shock
11/2020 - 01/2007
5Neointima
01/2020 - 07/2006
5Infections
06/2019 - 10/2007
4Inflammation (Inflammations)
10/2016 - 12/2010
4Hypoxia (Hypoxemia)
08/2014 - 07/2009
3Acute Kidney Injury (Acute Renal Failure)
12/2021 - 01/2014
3Necrosis
10/2021 - 05/2015
3Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
01/2021 - 01/2016
3Death (Near-Death Experience)
01/2020 - 02/2015
3Body Weight (Weight, Body)
01/2020 - 12/2018
3Infarction (Infarctions)
01/2019 - 09/2011
3Aortic Root Aneurysm
12/2017 - 02/2004
3Aortic Aneurysm (Aneurysm, Aortic)
11/2017 - 08/2005
3Shock
04/2015 - 06/2007
3Cardiovascular Diseases (Cardiovascular Disease)
01/2013 - 01/2007
3Pulmonary Hypertension
07/2011 - 08/2006
3Aneurysm (Aneurysms)
07/2006 - 11/2002
2Aortic Coarctation
01/2022 - 02/2014
2Stroke (Strokes)
01/2021 - 02/2012
2Hypertension (High Blood Pressure)
01/2021 - 12/2019
2Hypertrophy
01/2021 - 01/2018
2Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
08/2020 - 12/2012
2Pulmonary Embolism
04/2019 - 01/2012
2Atrial Remodeling
01/2019 - 01/2017
2Diabetes Mellitus
12/2018 - 05/2009
2Disease Progression
11/2018 - 10/2011
2Neoplasms (Cancer)
11/2016 - 06/2015

Drug/Important Bio-Agent (IBA)

6Glucose (Dextrose)FDA LinkGeneric
07/2021 - 05/2002
6Proteins (Proteins, Gene)FDA Link
10/2018 - 02/2008
5Fibrillin-1IBA
11/2021 - 11/2002
5DNA (Deoxyribonucleic Acid)IBA
11/2021 - 05/2015
5Matrix Metalloproteinases (MMPs)IBA
11/2021 - 12/2017
5Soluble Guanylyl CyclaseIBA
12/2018 - 08/2009
5BAY 58-2667IBA
01/2018 - 08/2009
5EnzymesIBA
01/2018 - 06/2009
5ZincIBA
05/2016 - 01/2013
4Potassium Channels (Potassium Channel)IBA
01/2022 - 11/2017
4SolutionsIBA
10/2021 - 04/2010
4Conditioned Culture MediaIBA
01/2021 - 01/2019
4Messenger RNA (mRNA)IBA
12/2018 - 08/2009
4bis(aspirinato)zinc(II)IBA
05/2016 - 12/2014
4Guanosine Monophosphate (5' Guanylic Acid)IBA
10/2015 - 06/2009
3Custodiol-N solutionIBA
10/2022 - 04/2010
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2022 - 03/2016
3Transcription Factor AP-1 (Transcription Factor AP 1)IBA
11/2021 - 12/2017
3Troponin T (Troponin T1)IBA
01/2021 - 01/2013
3Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
05/2017 - 06/2007
3Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2015 - 02/2011
3Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2015 - 08/2009
3Vardenafil Dihydrochloride (Levitra)FDA Link
06/2012 - 06/2009
23-nitrotyrosineIBA
10/2021 - 01/2021
2CanagliflozinIBA
07/2021 - 01/2019
2SodiumIBA
07/2021 - 01/2019
2salicylhydroxamic acid (SHAM)IBA
10/2020 - 12/2019
2dicarboxydine (DCD)IBA
01/2020 - 02/2015
2Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2020 - 09/2019
2AcidsIBA
01/2020 - 01/2019
2Dopamine (Intropin)FDA LinkGeneric
12/2019 - 10/2011
2OligodeoxyribonucleotidesIBA
09/2019 - 12/2017
2Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
10/2018 - 04/2011
2Caspase 3 (Caspase-3)IBA
10/2018 - 05/2015

Therapy/Procedure

23Heart Transplantation (Grafting, Heart)
01/2021 - 10/2007
19Transplantation
01/2021 - 10/2005
16Therapeutics
01/2019 - 11/2003
15Cardiopulmonary Bypass (Heart-Lung Bypass)
01/2019 - 03/2009
9Stents
01/2022 - 11/2003
6Coronary Artery Bypass (Coronary Artery Bypass Surgery)
10/2021 - 02/2007
6Catheters
10/2020 - 02/2012
6Heart-Assist Devices
10/2020 - 01/2014
6Replantation
01/2019 - 11/2002
5Extracorporeal Membrane Oxygenation
01/2022 - 03/2014
5Transcatheter Aortic Valve Replacement
01/2019 - 06/2012
5Decompression
06/2017 - 09/2009
5Thoracotomy
02/2014 - 11/2003
4Prostheses and Implants (Prosthesis)
01/2018 - 02/2007
3Length of Stay
06/2019 - 11/2003
3Extracorporeal Circulation
01/2016 - 12/2012
3Sternotomy
02/2007 - 08/2005
2Resuscitation
07/2022 - 12/2021
2Artificial Respiration (Mechanical Ventilation)
01/2021 - 05/2009
2Cannula
10/2020 - 08/2014
2Kidney Transplantation
11/2018 - 10/2011
2Renal Dialysis (Hemodialysis)
01/2018 - 01/2014
2Artificial Heart (Artificial Hearts)
11/2016 - 09/2015
2Lung Transplantation
11/2016 - 02/2015